New Look at RSV Infection: Tissue Clearing and 3D Imaging of the …
Furthermore, 3D imaging was also valuable to detect the cytoplasmic viral factories, also called inclusion bodies, a hallmark of RSV infection. Conclusions: Whole lung clearing and 3D deep imaging represents an unprecedented visualization method of infected lungs to allow insight into RSV pathophysiology and improve the 2D histology analyses.
New Look at RSV Infection: Tissue Clearing and 3D ...
Jan 28, 2021 · Whole lung clearing and 3D deep imaging represents an unprecedented visualization method of infected lungs to allow insight into RSV pathophysiology and improve the 2D histology analyses.
New images of RSV may expose stubborn virus's weak points
Oct 1, 2024 · Flash-freeze many RSV particles, and cryo-ET imaging will capture (nearly) all the virus's possible configurations from many different angles. These 2D images are combined to produce a...
New images of RSV may hold key to unlocking new treatments
Oct 31, 2024 · As described in their recent publication in Nature, Wright’s research team produced high-resolution 3D images of the virus and the proteins that determine its structure. Utilizing a technique called cryo-electron tomography, in which infectious RSV particles are frozen at cryogenic temperatures, they were able to inspect the structure of RSV ...
High-resolution images of RSV may expose stubborn virus's weak …
Oct 1, 2024 · New images of the virus from researchers at the University of Wisconsin–Madison may hold the key to preventing or slowing RSV infections.
(PDF) New Look at RSV Infection: Tissue Clearing and 3D ...
Jan 28, 2021 · Methods: By combining tissue clearing, 3D microscopy and image processing, we developed a novel visualization tool of RSV infection in undissected mouse lungs. Results: Whole tissue analysis...
Study: Researchers Reveal New Images of RSV, Offering Further …
Oct 19, 2024 · Cryo-electron tomography provided high-resolution images of RSV proteins, revealing structural details crucial for viral-host interactions. RSV M and F proteins play significant roles in viral assembly and host cell interaction, offering potential drug targets.
Respiratory syncytial virus entry and how to block it
Feb 5, 2019 · Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract disease in young children and elderly people. Although the virus was isolated in 1955, an effective RSV...
New look at RSV infection : tissue clearing and 3D imaging of …
Dec 23, 2020 · Furthermore, 3D imaging was also valuable to detect the cytoplasmic viral factories, also called inclusion bodies, a hallmark of RSV infection. Conclusions Whole lung clearing and 3D deep-imaging represents an unprecedented visualization method of infected lungs to allow insight into RSV pathophysiology and improve the 2D histology analyses.
The Morphology and Assembly of Respiratory Syncytial Virus
Aug 20, 2018 · RSV is a pleomorphic enveloped RNA virus in the Pneumoviridae family. Recently, the three-dimensional (3D) structure of purified RSV particles has been elucidated, revealing three distinct morphological categories: spherical, asymmetric, and filamentous.
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