(BPT) - TGCT stands for tenosynovial giant cell tumor, which is also sometimes called pigmented villonodular synovitis (PVNS) or giant cell tumor of the tendon sheath (GCT-TS). To most of us this ...

TGCT is caused by dysregulation of the CSF1 gene leading to overproduction of CSF1. TGCT is also known as giant cell tumor of the tendon sheath (GCT-TS) or pigmented villonodular synovitis ...

Treatments for both TGCT and cancer, Stern noted, can result in similar side effects, such as nausea, facial swelling, and changes to the skin and hair. “One thing is there's no metastasis or no ...

And I don't know if it was because nobody's familiar with TGCT because it's so rare.” Sierra eventually received a diagnosis, and treatment via surgery. In a conversation with CURE® as part of the ...

TGCT, also known as giant cell tumor of the tendon sheath (GCT-TS) or pigmented villonodular synovitis (PVNS), is a rare, typically benign tumor (not cancerous) occurring in or around a joint.

TGCT is a rare, non-cancerous tumour affecting the joints, tendons, or joint tissue. It is linked to a CSF1 gene mutation that causes abnormal cell growth, joint pain, stiffness, and inflammation.

TGCT arises from dysregulation of CSF1, leading to overproduction of the CSF1 protein and accumulation in the synovial covering of joint spaces and in tendon sheaths.Affected patients have ...

IMPLICATIONS: TGCT is largely treatable, but treatment usually involves have the afflicted testis removed.The authors also suggest that cocaine may play a role in opposing the effects of THC.

(RTTNews) - Deciphera Pharmaceuticals, Inc. (DCPH) Monday announced positive top-line results from the pivotal Phase 3 MOTION study of its investigational drug Vimseltinib in patients with ...

Dr Ozren Bogdanovic and his team discovered that unusually high levels of DNA repeats of the sequence 'TGCT' in the zebrafish genome undergo a modification called methylation, which may change the ...