The Big Ten on CBS will feature a top-20 matchup in Week 4 as the No. 18 Michigan Wolverines host the No. 11 USC Trojans on Saturday for a 3:30 p.m. ET kickoff. The defending national champions were blown out at home by Texas but could get themselves back into the College Football Playoff mix with a run to the Big Ten Championship Game.

Our staff provides their prediction and analysis as Florida State tries to prevent its first 0-4 start since 2021.

Cal leaves Tallahassee with its first ACC victory, and first win over the Seminoles in program history. While FSU will show improvement defensively, particularly along the defensive front, a returning Ott will power the Golden Bears to victory on the ground.

Both teams are unbeaten and can establish themselves as clear-cut College Football Playoff contenders with a victory. Tennessee is a 6.5-point road favorite in the Week 4 college football odds via the SportsLine Consensus,

Predicting the over/under on Malik Benson’s receiving yards, Fernando Mendoza’s passing yards, and total game score

Miami and South Florida meet in a Sunshine State battle between two teams with potent offenses. Cam Ward has emerged as the favorite to win the Heisman Trophy,