Osteoclasts, bone-degrading cells, operate under the control of osteoblasts, bone-forming cells. But recent studies have suggested that osteoclasts don't just passively carry out orders—they in ...

Both osteoblasts and osteoclasts are necessary for fracture repair. While osteoblasts are known to control the formation and activity of osteoclasts, the inter-cellular signaling involved in this ...

Osteoclasts clear the way for another type of cell - the osteoblast. The osteoblast builds new bone. Osteoclasts and osteoblasts normally are in balance. But to treat diseases that result in bone loss ...

Remodeling involves both osteoclasts and osteoblasts, which form the basic multicellular unit. 20 Since osteoblasts are known to differentiate from mesenchymal precursors in the bone marrow, 3 the ...

Osteoblasts act in a group to make bone over the course of several months. ... Using this method, they explored the interplay between bone-destroying osteoclasts and bone-forming osteoblasts.

In a study published recently in Communications Biology, researchers led by Kanazawa University explain how a tiny fish could help end painful metabolic and genetic bone diseases.

Panel A shows osteoclasts and osteoblasts in normal bone (toluidine blue, ×100). The large osteoclast is actively resorbing bone. Osteoblasts are small, cuboid cells that actively lay down bone ...

Further experiments in a co-culture system with osteoblasts and osteoclasts confirmed iSN40's dual action. The results ...