Total hip replacement is routinely recommended for severe hip osteoarthritis, but data from randomized trials are lacking ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when ...

Medication abortion, with a combination of mifepristone and misoprostol, is highly effective and safe. However, there is insufficient evidence on efficacy and safety at very early gestations ...

In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and ...

In patients with out-of-hospital cardiac arrest, the effectiveness of drugs such as epinephrine is highly time-dependent. An intraosseous route of drug administration may enable more rapid drug ...

A tool used by the government for substance-use surveillance has consistently reported low rates of OUD. But the survey excluded a large group of Americans with OUD: people who take opioids as ...

Jose Figueroa is an associate professor of health policy and management at the Harvard T.H. Chan School of Public Health and an assistant professor of medicine at Harvard Medical School.

Read before the Philadelphia County Medical Society, October 17, 1883. Physician to the Philadelphia Hospital for Skin Diseases, Lecturer and Instructor on Diseases of the Skin in the Summer ...