Coralie Fargeat tells IndieWire about the feelings of insecurity, of passing age 40, that led to her new film 'The Substance,' starring Demi Moore

Starring alongside Demi Moore is Margaret Qualley, as the women play two sides of the same aerobics instructor. Moore is a recently fired 50-year-old named Elisabeth Sparkle, who begins injecting herself with a serum to create a younger,

It's not long before Demi and her doppelganger are at each other's throats. Complications ensue when Sue is hired by Elisabeth's old boss (Quaid is scarily hilarious as Harvey) to star in a new workout show called "Pump It Up.

The provocative new film “The Substance,” about an aging celebrity (Demi Moore) who takes an illicit drug to be young again, opened on September 20 following its May premiere in competition at the Cannes Film Festival,

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

Demi Moore’s new film “The Substance” recently received a 13-minute standing ovation at Cannes, proving her worth as one of the most decorated actresses in Hollywood. Moore was also mentioned by Variety and People magazine as a sure nominee for the Oscars 2025.