The team tackled a critical challenge in treating multiple myeloma-a blood cancer where malignant plasma cells accumulate in bone marrow, leading to debilitating bone lesions in 80% of patients.

A team of researchers has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple myeloma patients. The findings showcase a ...

We described the first case reported in the literature of multiple myeloma in a young African woman with Systemic lupus and Sjögren Syndrome. The clinician should consider multiple myeloma in young ...

Researchers at Hospital for Special Surgery (HSS) have pinpointed a cellular target that could enhance the way osteoporosis and other metabolic bone diseases are diagnosed and treated. The findings, ...

Throughout our lives, our bones are continuously remodeled to maintain strength, repair injuries and adapt to new stresses.

Max Planck Researchers discover a third vascular player in bone remodeling. Prof. Dr. Ralf Adams [email protected] ...

Bone mass and strength are maintained by the bone remodeling cycle involving the integrated actions of osteocytes, osteoclasts and osteoblasts. Current therapies for the prevention and treatment ...

Interestingly, Malat1 does not directly affect osteoclastogenesis but inhibits osteoclastogenesis in a non-autonomous manner in vivo via integrating crosstalk between multiple cell types, including ...

The imbalance occurs between osteoblasts, responsible for bone formation, and osteoclasts, which break down bone tissue. This disrupted process results in weakened bones and increased ...