eLife

TSvelo: Comprehensive RNA velocity by modeling the cascade of gene regulation, transcription and splicing

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...
eLife

Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves learned motor execution

This valuable study addresses a critical and timely question regarding the role of a subpopulation of cortical interneurons (Chrna2-expressing Martinotti cells) in motor learning and cortical dynamics ...

Automated systems decide which homeless Philadelphians get housing and who stays on the street – often in ways that feel arbitrary to those waiting

Supportive housing combines subsidies with wraparound social services to help people stay off the streets. But demand far ...