Glycolytic waves drive and fuel cancer cell migration. The image, captured with a high-powered microscope over 9-minute intervals, is color-coded from early to late time points showing wave activity ...

Hemifusomes are fused vesicles, or sacs of fluid, that were previously unknown to exist inside cells. They were discovered ...

In the complex world of neuroscience, Huntington's disease remains a cruel mystery. It slowly strips away a person’s ability ...

Like all complex organisms, every human originates from a single cell that multiplies through countless cell divisions.

Researchers from the National University of Singapore (NUS) have solved a 60-year-old mystery in bacterial cell envelope ...

In a twist, researchers at the University of Virginia and the National Institutes of Health uncovered a new organelle, dubbed ...

But if the membrane was cholesterol-depleted, the pearls didn’t swell, and the signaling speed didn’t improve. That indicates a tight relationship between axon shape, membrane composition, and signal ...

Hodgkin, A.L. and Huxley, A.F. (1952) The Dual Effect of Membrane Potential on Sodium Conductance in the Giant Axon of Loligo. The Journal of Physiology, 116, 497-506.

Foust, A.J., Yu, Y., Popovic, M., Zecevic, D. and McCormick, D.A. (2011) Somatic Membrane Potential and Kv1 Channels Control Spike Repolarization in Cortical Axon Collaterals and Presynaptic Boutons.

Axons in brain cells may resemble “pearls on a string” rather than tubes. A new study highlights how axon shape impacts brain signaling and offers new insights into neuron structure. Axons in brain ...

Membrane mechanics dictate axonal pearls-on-a-string morphology and function. Nature Neuroscience, 2024; DOI: 10.1038/s41593-024-01813-1 ...

Electron microscope image of a cryo-preserved axon shows details of its pearls-on-a-string nanomorphology. Credit: Quan Gan and Mitsuo Suga view more Credit: Quan Gan and Mitsuo Suga WOODS HOLE, Mass.