A simulation study demonstrated the adequacy of our formulas in finite sample size settings. An application to a clinical trial to evaluate the treatment effect on prevention of COPD exacerbation is ...

Comparing results of a single-arm early-phase trial to those of a rigorously matched HCT ECA yielded insights regarding comparative efficacy prior to a randomized controlled trial. The effect size ...

We focus on the randomised controlled trial, but the guide also applies to other study designs. Topics included in the REPORT guide cover reporting checklists, trial report structure, choice of title, ...

A sample size of 160 individuals (80 to each study arm) for this trial was determined on the basis of the F -test to detect a time by treatment group interaction effect at the 5% significance level ...

We conducted an international, double-blind, parallel-group, randomized, placebo-controlled trial to evaluate the effect of supplemental enteral glutamine on the time to discharge alive in ...

Ivermectin to Control Malaria — A Cluster-Randomized Trial Results A total of 84 clusters comprising 28,932 eligible participants underwent randomization.

Preimplantation genetic testing in fertility treatment can detect chromosomal abnormalities in embryos leading to higher live birth rates in IVF.