Mice lacking the extracellular matrix protein tenascin-C showed a reduced ability to repair muscular damage compared to controls.

The extracellular matrices (ECMs) of connective tissues are crucial for normal development and tissue function, and mutations in ECM genes result in a wide range of serious inherited disorders. These ...

Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of glycosaminoglycan chains that are covalently attached to a ...

Scientists at the University of Helsinki have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Extracellular ...

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal ...

Jesse Roman, Rhonda M. LaChance, Thomas J. Broekelmann, Charlotte J. R. Kennedy, Elizabeth A. Wayner, William G. Carter and John A. McDonald Cells interact with extracellular fibronectin (FN) via ...

New images are providing the first visual evidence of a long-postulated physical link by which genes can receive mechanical cues from its microenvironment. Created by integrating six different imaging ...

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee ...