Somatic testing analyzes genetic material in specific cells or tissues to identify acquired mutations, revolutionizing oncology by enhancing diagnosis, prognosis, and treatment strategies. This ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Biological aging undeniably affects human cognitive function. 1 However, how this happens—the underlying factors, interactions, and processes—remains unclear. He and his team want to understand how ...