Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...
In a recent study posted to the bioRxiv* preprint server, researchers discovered compounds able to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain 1 (Mac1) and ...
Hsp90 plays a central role in cell homeostasis by assisting folding and maturation of a large variety of clients. It is a homo-dimer, which functions via hydrolysis of ATP-coupled to conformational ...
ATP-ADP exchange was estimated in the presence of plasma membrane H+-ATPase of oat (Avena sativa) roots partially purified with Triton X-100 by measuring [14C]ATP formation from [14C]ADP. Most studies ...
ATP is the main source of energy for most cellular processes. The building blocks of ATP are carbon, nitrogen, hydrogen, oxygen, and phosphorus. Because of the presence of unstable, high-energy bonds ...
Biochemical kinase assay kits from BellBrook Labs provide a simple tool for measuring kinase activity in a high throughput format. Kinase enzymes transfer phosphate groups from ATP to a substrate ...
Over the past 20 years, the fight against cancer has been prosecuted with increasing zeal by protein kinase inhibitors. More numerous, more sophisticated, and better targeted than ever, these ...
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