Many mitochondrial diseases have been difficult to study and treat due to the inherent challenges in accessing mitochondrial DNA (mtDNA). Now, researchers have optimized mitochondrial-targeted ...

One study reported 8 live births from 22 women with pathogenic mtDNA variants who underwent mitochondrial donation through pronuclear transfer. None had signs of mitochondrial disease and heteroplasmy ...

Cirrhotic cardiomyopathy (CCM) is a significant complication of cirrhosis, but its progression and underlying mechanisms ...