Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...

Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies"). New research led by Boston Children's Hospital challenges the current ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide. Additionally, about one-fourth of the world's population carries Mycobacterium ...

Explore the complexities of tauopathies and how new research could change their diagnosis and treatment approaches.

Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies"). New research led by Boston Children's Hospital challenges the current ...

Whole blood derived from six adult donors who were inoculated with BCG in their childhood was cultured with MDP1 alone, MDP1 in combination with G9.1, or in combination with the negative form of ...

Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.

Cognitive tasks, such as learning and memory, require rapid changes to proteins at synapses, such as protein synthesis, degradation, and trafficking. How protein post-translational modifications ...

A new study published in the journal Cell Death & Disease by researchers at the University of Alabama at Birmingham has identified a potential therapeutic target for ...