Replicating bacterial DNA relies on accordion-like folds to separate, researchers discover

When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...

Maize mysteries: Scientists uncover new information on how DNA works in maize

Maize serves as a vital model species for advancing our understanding of plant biology, yet many mysteries remain about the ...

Scientists create the most detailed digital simulation of life ever attempted

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

Why simulating an entire cell cycle took years, multiple GPUs and six days per run

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell division—scientists have opened a new frontier of computer vision into the ...
Kaleido Scope

New model for replication of BKPyV virus, a major cause of kidney transplant failure

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...
The Scientist

DNA Polymerase Works in Short Bursts Rather than One Long Stretch

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...