The human body has 78 organs and each one performs a variety of important functions. While it's possible to live without organs like the appendix, gallbladder, or spleen, several of our organs are ...

Nephrotic syndrome is a clinical entity defined by heavy proteinuria, hypoalbuminemia, hyperlipidemia, and edema, stemming from various glomerular diseases. Diagnosis requires a comprehensive ...

Approximately 1 in 11 patients with kidney failure requiring replacement therapy have inherited kidney diseases or congenital anomalies of the kidney and urinary tract. Genetic testing is warranted to ...

PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...

Diseases of the circulatory system and infection top the list of causes of non-elective hospitalizations among patients with CKD. Patients with nondialysis-dependent chronic kidney disease (CKD) are ...

Kidneys can be injured by a number of reasons. In the United States, more than 10% of adults are estimated to have kidney disease, although most don’t know it because early signs are often missed.

Your kidneys work tirelessly every day, filtering approximately 120 to 150 quarts of blood to produce about 1 to 2 quarts of urine. These vital organs remove waste products, excess water, and toxins ...