Regulation of osteoclastogenesis by factors from osteoblasts/stromal cells interacting with receptors on hematopoietic osteoclast precursor cells. RANK-L: receptor activator of NF-kappaB ligand ...

A team of researchers from the Translational Oncology Research Centre (TORC) of Vrije Universiteit Brussel (VUB), in ...

The imbalance occurs between osteoblasts, responsible for bone formation, and osteoclasts, which break down bone tissue. This disrupted process results in weakened bones and increased ...

Discovery of Type R capillaries: key player in bone remodeling, ageing, osteoporosis treatment and bone regeneration.

The team tackled a critical challenge in treating multiple myeloma-a blood cancer where malignant plasma cells accumulate in bone marrow, leading to debilitating bone lesions in 80% of patients.

A team of researchers has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple myeloma patients. The findings showcase a ...

The imbalance occurs between osteoblasts, responsible for bone formation, and osteoclasts, which break down bone tissue. This disrupted process results in weakened bones and increased ...

Bone mass and strength are maintained by the bone remodeling cycle involving the integrated actions of osteocytes, osteoclasts and osteoblasts. Current therapies for the prevention and treatment ...