The orbitofrontal cortex (OFC), a subsection of the brain's frontal lobe, is known to play a part in value-based decision-making, the process of mentally weighing the outcome of different decisions ...

Have you ever noticed how you can suddenly hear your refrigerator humming in the background when you focus on it? Or how the sound of your name instantly catches your attention even in a noisy crowd?

Newly identified brain cells evolved along the theme, "Life is uncertain; Eat dessert first." The neurons, located in the front part of the brain, are most active when the outcome of a decision is ...

Depression imposes a major global socioeconomic burden, and current pharmacotherapies face several limitations, including slow efficacy, adverse effects, and non-response rates of up to 55%, ...

A new study linked chronic pain to activity in the orbitofrontal cortex, an area involved in emotion regulation, self-evaluation and decision making. By Priyanka Runwal Researchers have for the first ...

The same areas of the brain-the medial orbitofrontal cortex-are engaged when people receive a reward or avoid a negative outcome. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy ...