In a big leap for genomics, Google on Wednesday unveiled a powerful AI model that predicts how single DNA mutations affect the complex machinery regulating gene activity. Named AlphaGenome, the tool ...

Researchers have changed the way to look at DNA. They show that DNA is much more than a linear sequence of building blocks; it has a 3D structure that influences the variation of human genome-wide ...

Cells have to protect the genome, and there are mechanisms in place to repair DNA damage that does arise. But sometimes those mechanisms fail. New research reported in Nature Communications has ...

Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments and diagnostics easier and quicker, new research has found. Working with ...

Geneticists looking inside the nuclear genome for mutations that contribute to disease have long relied on a principal known as constraint modeling, which allows researchers to assess the degree of ...

Tsukuba, Japan—Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models ...

Cancer genomes are the result of diverse mutation processes that have often accumulated over decades. Scientists have analyzed the molecular evolution of tumors after exposure to mutagenic chemicals.

Between any two people, there are likely to be at least 10 million differences in the genetic sequence that makes up their DNA. Most of these differences don't alter the way cells behave or cause ...

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the ...

Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little organelles are very special, because they also carry their own tiny little ...