β-Sheet-rich α-synuclein (αS) aggregates characterize Parkinson’s disease (PD). αS was long believed to be a natively unfolded monomer, but recent work suggests it also occurs in α-helix-rich ...

Starting with billions of molecules of monomer in a reactor, heat and pressure are applied in the presence of catalysts, causing one of the monomer double bonds to rearrange into two "half-bonds," one ...

Generally, in protein and peptide analyses, knowing a molecule’s oligomeric state is useful in determining whether the protein exists in its biologically active form. To this end, the first step ...