Schematic representation of axonal transport vesicles (blue) carrying presynaptic proteins (SV and AZ proteins). Kinesin motor proteins (KIF1A) attach these vesicles and carry them along the axons to ...

The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature Communications that determined that liquid-liquid phase separation plays a key role ...

Scientists have taken a major step in understanding how animal brains make decisions, revealing a crucial role for electrical synapses in 'filtering' sensory information. The new research demonstrates ...

They used synapses from the fruit fly drosophila, which compares remarkably closely to synapses in humans. The results showed that two variations of a protein called Unc13 work separately to regulate ...

Researchers from The University of Texas at Dallas’ Center for Advanced Pain Studies (TX, USA) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Synapse labeling strategies involve marking synaptic contact sites with different fluorescent proteins in the pre- and postsynaptic compartments. The interface between these contacts is also labeled, ...

Whether picking up a small object like a pen or coordinating different body parts, the cerebellum in the brain performs essential functions for controlling our movement. Researchers investigated how a ...

Researchers from The University of Texas at Dallas' Center for Advanced Pain Studies (CAPS) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...