One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Animal models are required to study mechanisms of early cardiovascular development. The chick embryo has been used as a model for many decades because the embryonic chick heart resembles the ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...