Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, plays a ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines. DNA ...

In the DNA fiber assay used in this study, cells labeled with IdU (green) and CldU (red) nucleotide analogs were sorted into substages of S phase before being subjected to the DNA fiber assay. This ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...