A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the ...

Cancer cells rewire their metabolism to support rapid proliferation, survival under stress and metastatic spread. This reprogramming encompasses a shift from mitochondrial oxidative phosphorylation to ...

Thyroid cancer cells undergo profound metabolic reprogramming to support rapid proliferation, survival under stress and metastatic spread. A hallmark of this reprogramming is the shift from ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

A new review article highlights the expanding importance of glutamine metabolism in shaping the tumor microenvironment, offering fresh perspectives on how metabolic interactions influence cancer progr ...

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer ...

A recent study has demonstrated the power of metabolic engineering in enhancing the antitumor activity of chimeric antigen receptor (CAR) macrophages (CAR-Ms) in solid tumors. By overexpressing the ...

A new study led by researchers at Huntsman Cancer Institute at the University of Utah (the U) shows that regular exercise may do more than help colon cancer patients feel better—it may actually change ...

GLP-1 drugs commonly used for weight loss and diabetes decreased the risk of cancer spreading in patients with several ...

UH engineers helped develop an mRNA-based strategy that boosts cancer-fighting T cells and, in mouse studies, helped ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

In tumors of active patients: Genes tied to cancer progression (angiogenesis, epithelial-mesenchymal transition) were less active. Genes involved in energy production (oxidative phosphorylation) were ...