Atomic Force Microscopy-based SMFS is widely used due to its high force sensitivity and spatial resolution. In this technique, a biomolecule is attached between a surface and an AFM cantilever. As the ...

The application of single-molecule force spectroscopy has revolutionised our understanding of protein folding and intermolecular interactions by allowing the direct interrogation of folding pathways ...

Fluidic force microscopy (FluidFM) is a cutting-edge technique that integrates atomic force microscopy (AFM) with nanofluidics, enabling simultaneous imaging and manipulation of biological samples at ...

In a recent article published in Nature Nanotechnology, researchers introduced an approach in single-molecule spectroscopy, significantly improving the ability to probe quantum transitions in ...

When it comes to analyzing living cells, challenging biological samples and thick, multilayer tissue samples require purposefully designed instrumentation. BioAFMs are ideal when it comes to these ...

Temporary protein-protein bonds are essential for processes including enzymatic reactions, antibody binding, and response to medication. Being able to accurately characterize these bonds is important ...

Invented 30 years ago, the atomic force microscope has been a major driver of nanotechnology, ranging from atomic-scale imaging to its latest applications in manipulating individual molecules, ...