Shares of planemaker Boeing lost 7% premarket after an Air India aircraft with more than 200 people crashed in India's western city of Ahmedabad, and aviation tracking site Flightradar24 said the plane was a Boeing 787-8 Dreamliner.

Wall Street's main indexes opened lower on Thursday as signs of rising tensions in the Middle East hurt risk sentiment and investors sought more clarity on Washington's recent trade deals with China.

Wall Street stocks mostly rose Wednesday as investors welcomed cooler US inflation data and a China-US agreement aimed at lowering trade tensions. Investors have worried that a tariff-driven surge in inflation could hinder the Federal Reserve from lowering interest rates to counter the slowdown in growth.