Israel’s attack on Iran was long in the making – the result of years of meticulous planning by Israel and days of high-stakes talks between Tel Aviv and Washington, officials told CNN.

Israel’s leader and President Trump appeared to bet they can persevere, but other world leaders warned of unintended outcomes in a volatile region.

Israeli emergency services have said at least two people were killed in the strikes and dozens of people are injured.

VATICAN CITY (Reuters) -Pope Leo appealed on Saturday for authorities in Iran and Israel to act with "reason" after recent airstrikes and to pursue dialogue. He told an audience in St. Peter's Basilica he was following the situation with "great concern."

Interviews with half a dozen senior Iranian officials show that they were not expecting Israel to strike before another round of talks.

The explosive conflict between Israel and Iran is roiling the Middle East – and raising questions about whether the world is moving ahead without the U.S. Colonel Jack Jacobs, Anthony Fisher, Pablo Torre,

Israel and Iran opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday that set off explosions in the Iranian capital of Tehran. Israel said it targeted nuclear and military facilities,