In the lawsuit filed early Friday in federal court in Boston, the Ivy League school called out the government’s ban as a violation of the Constitution and warned that it would have an “immediate and devastating effect for Harvard and more than 7,000 visa holders.”

Harvard University is locked in a legal battle with the Trump administration after being barred from enrolling international students. Homeland Security cited national security risks, prompting Harvard to sue.

The president’s fight threatens to leave the school a different place even if it ultimately wins its lawsuits.